Anemia due to CKD
Correction phase: Max: 720 IU/kg/wk. SC
Initially 3 x 20 IU/kg/wk. May be increased every 4 wk by 3 x 20 IU/kg/wk if increase of Hb is not adequate. Maintenance phase: Administer wkly dose as a single inj or in 3 or 7 divided doses, may be switched to once every 2 wk. IV
Initially 3 x 40 IU/kg/wk. May be raised after 4 wk to 80 IU/kg 3 times/wk & by further increments of 20 IU/kg 3 times/wk at mthly intervals, if needed. Maintenance phase: Initially reduce to ½ of the previously administered amount, then adjust individually at 2-4 wk intervals. Symptomatic anemia in cancer patients receiving chemotherapy
Administer wkly dose as a single inj or in 3-7 divided doses SC. Initially 30,000 IU/wk or approx 450 IU/kg/wk. Double wkly dose if Hb value has not increased by at least 1 g/dL. Max: 60,000 IU/wk. Increasing the amount of autologous blood
Single dose administered twice wkly over 4 wk. Max: 1,600 IU/kg/wk for IV or 1,200 IU/kg/wk for SC. Prevention of anemia of prematurity
3 x 250 IU/kg/wk SC, starting as early as day 3 of life for 6 wk. Anemia in myelodysplastic syndromes including other ineffective erythropoiesis
Initially 30,000 IU/wk SC. Treatment is indicated if Hb value ≤10 g/dL. Hb levels should not exceed 12 g/dL. Double wkly dose (60,000 IU wkly), if Hb level increase <1 g/dL from baseline Hb level & Hb level <12 g/dL after 6-8 wk.