Selrotine

Selrotine

sertraline

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical
Concise Prescribing Info
Contents
Sertraline (equiv to sertraline HCl 55.953 mg)
Indications/Uses
Treatment of major depressive disorder (MDD), obsessive compulsive disorder (OCD), panic disorder w/ or w/o agoraphobia, social anxiety disorder (SAD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD).
Dosage/Direction for Use
Adult MDD Initially: 50 mg once daily. OCD Initially: 50 mg once daily. Panic disorder Initially: 25 mg once daily, increased after 1 wk to 50 mg daily. SAD Initially: 25 mg once daily, increased after 1 wk to 50 mg daily. PTSD Initially: 25 mg once daily, increased after 1 wk to 50 mg daily. Maintenance: Dose may be increased, if necessary, in increments of 50 mg daily at intervals of at least a wk to a max of 200 mg daily. PMDD Initially: 50 mg once daily, either daily throughout the menstrual cycle or limited to the luteal phase of the menstrual cycle. Maintenance: Dose may be increased, if necessary, by 50 mg each menstrual cycle up to max of 150 mg daily when dosing daily throughout the menstrual cycle or 100 mg daily when dosing during the luteal phase of menstrual cycle.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Concomitant use w/ MAOIs & pimozide.
Special Precautions
Serotoninergic syndrome. Increased suicide risk in early stages of recovery. History of mania/hypomania & bleeding disorders. Syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Increase in ALT/AST. Avoid alcohol.
Adverse Reactions
Edema, hypotension, MI, precordial/substernal chest pain, euphoria, headache, hallucination, hyperesthesia, leg cramps, migraine, pustular rash, skin discoloration, vasculitis, Stevens-Johnson syndrome, esophagitis, increased saliva, teeth grinding, aphthous stomatitis, colitis, atrophic vaginitis, female breast pain, breast enlargement, dysuria, nocturia, polyuria, urinary incontinence, cystitis, arthrosis, dystonia, muscle cramps, muscle weakness, bronchospasm, epistaxis, apnea, bradypnea, hemoptysis, hyperventilation, hypoventilation.
Drug Interactions
Cytochrome P450, other SSRIs or SNRIs, MAOIs, pimozide, thioridazine or mesoridazine, warfarin, lithium, NSAIDs, aspirin or other drugs affecting coagulation, St. John’s wort.
MIMS Class
ATC Classification
N06AB06 - sertraline ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Selrotine tab 50 mg
Packing/Price
3 × 10's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in