Treatment of chronic liver diseases w/ bile flow impairment (eg, primary biliary cirrhosis or schlerosing cholangitis, cystic fibrosis-related cholestasis). Dissolution of cholesterol gallstones in patients w/ uncomplicated radiolucent gallstone disease. Prevention of gallstone formation in obese patients experiencing rapid wt loss.
Dosage/Direction for Use
Adult & elderly w/ diseases other than fibrosis 10-15 mg/kg/day in 2-4 divided doses. Dissolution of cholesterol gallstone 8-10 mg/kg body wt/day in 2-3 divided doses. Prevention of gallstone formation 300 mg bid.