Infuse IV at initial rate of 0.46-0.92 mL/kg/hr for 20-30 min; may be increased gradually to a max of 1.85 mL/kg/hr. Prevention of hepatitis B re-infection after liver transplantation for hepatitis B-induced liver failure Adult
10,000 IU on the day of transplantation perioperative; then 2,000-10,000 IU/day for 7 days & as necessary. Childn
10,000 IU/1.73 m2
BSA. Immunoprophylaxis of hepatitis B: Prevention of hepatitis B in case of accidental exposure in non-immunised subjects
At least 500 IU w/in 24-72 hr of exposure. Immunoprophylaxis of hepatitis B in haemodialysis patients
8-12 IU/kg w/ a max of 500 IU every 2 mth until seroconversion following vaccination. Immunoprophylaxis of hepatitis B: Prevention of hepatitis B in the newborn of a HBV carrier-mother, at birth or as soon as possible after birth
30-100 IU/kg. IM route is preferred whenever repeated administration is required to achieve seroconversion after vaccination.