Vesimycin

Vesimycin

mitomycin

Manufacturer:

Naprod Life Sciences

Distributor:

Atlanta Medicare
Concise Prescribing Info
Contents
Mitomycin
Indications/Uses
Disseminated adenocarcinoma of stomach or pancreas w/ other chemotherapeutic agent therapy & as palliative treatment when other modalities fail.
Dosage/Direction for Use
Hematological recovery from previous chemotherapy 20 mg/m2 IV as a single dose at 6-8 wk interval.
Contraindications
Hypersensitivity or history of idiosyncratic reaction. Patients w/ thrombocytopenia, coagulation disorder or increased bleeding tendency due to other causes.
Special Precautions
Monitor platelet & WBC count, differential & Hb repeatedly during therapy & at least 8 wk. Withhold further therapy if platelet count & WBC are below 100,000/mm3 & 4,000/mm3, respectively. Pregnancy.
Adverse Reactions
Bone marrow & renal toxicity; cellulitis at inj site, stomatitis, alopecia, delayed erythema &/or ulceration; dyspnea w/ nonproductive cough & radiographic evidence of pulmonary infiltrates; microangiopathic hemolytic anemia (hematocrit <25%), thrombocytopenia (<100,000/mm3), irreversible renal failure (serum creatinine 1.6 mg/dL); fever, anorexia, nausea, vomiting; headache, blurred vision, confusion, drowsiness, syncope, fatigue, edema, thrombophlebitis, hematemesis, diarrhea, pain.
ATC Classification
L01DC03 - mitomycin ; Belongs to the class of other cytotoxic antibiotics. Used in the treatment of cancer.
Presentation/Packing
Form
Vesimycin powd for inj 2 mg/mL
Packing/Price
1's
Form
Vesimycin powd for inj 10 mg/mL
Packing/Price
1's
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