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Chỉ định và Liều dùng
Oral
Hyperprolactinaemia Adult: 12 mg daily in divided doses, up to 24 mg daily in hyperprolactinaemic men.
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Chống chỉ định
Lactation (discontinue from the 1st day of treatment).
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Thận trọng
Pregnancy may occur during treatment for amenorrhoea-galactorrhoea, even without resumption of menstruation. Perform pregnancy test every 20 days and discontinue treatment. Nonhormonal contraceptives may be used.
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Tác dụng không mong muốn
Nausea, vomiting, insomnia, drowsiness, anxiety, dizziness, weakness.
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Tác dụng
Description:
Mechanism of Action: Metergoline, an ergot derivative, is a dopamine agonist with actions similar to bromocriptine. It is also a serotonin antagonist. It appears to take part in hypothalamic-pituitary neuroendocrine control, stimulating adrenocorticotropic hormone and prolactin release. Pharmacokinetics: Absorption: Well-absorbed (oral). Metabolism: Extensively hepatic. Excretion: Via faeces (70-80%). |
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Phân loại MIMS
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Đăng xuất
