Hypersensitivity reactions (eg, urticaria, papular urticaria, rash) following administration. Do not inj into areas w/ tender, bruised, erythematous, or hardened skin. Should not be used to treat acute asthma exacerbations; seek medical advice if asthma remains uncontrolled or worsens after treatment initiation. Not recommended to abruptly discontinue corticosteroids after initiation of Fasenra therapy. Patients w/ pre-existing helminth infections. Avoid use during pregnancy. Lactation. Childn 5-18 yr.