Renal Cell Carcinoma (RCC): CABOMETYX is indicated as monotherapy for advanced renal cell carcinoma: as first line treatment of adult patients with intermediate or poor risk (see Pharmacology: Pharmacodynamics under Actions); in adults following prior vascular endothelial growth factor (VEGF)-targeted therapy (see Pharmacology: Pharmacodynamics under Actions).
CABOMETYX, in combination with nivolumab, is indicated for the first-line treatment of advanced renal cell carcinoma in adults (see Pharmacology: Pharmacodynamics under Actions).
Hepatocellular Carcinoma (HCC): CABOMETYX is indicated as monotherapy for the treatment of hepatocellular carcinoma (HCC) in adults who have previously been treated with sorafenib.