Not to be used for septic syndrome or septic shock. Not be used for management of head injury or stroke. Immunosuppressant effects/increased susceptibility to infections, parasitic infections, impaired immune responsiveness, latent TB or tuberculin reactivity, allergic reactions, hypothalamic-pituitary adrenal (HPA) suppression, unusual stress, Cushing's disease, hypothyroidism, DM, existing or previous history of severe affective disorders, seizure disorders, epilepsy, myasthenia gravis, osteoporosis, glaucoma, ocular herpes simplex, prolonged use, existing CV risk factors, CHF, recent MI, HTN, ulcerative colitis, perforation, abscess or other pyogenic infections, diverticulitis, fresh intestinal anastomoses, peptic ulceration, acute pancreatitis. Avoid abrupt w/drawal. Concomitant use w/ aspirin, NSAIDs, cardioactive drugs. Renal insufficiency. Pregnancy & lactation. Growth retardation in childn. Childn <2 yr. Infant, not to be used in neonate. Elderly.