Amlotitan

Amlotitan

Manufacturer:

GXI

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Losartan K 50 mg, amlodipine besilate 5 mg
Indications/Uses
Mild to moderate HTN in case of inadequate control w/ monotherapy.
Dosage/Direction for Use
1 tab daily, may increase to 2 tab daily.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Losartan: Renal artery stenosis. Hypotension in patients w/ vol depletion. Monitor serum K conc. Renal & hepatic impairment. Lactation. Amlodipine: Hypotension, poor cardiac reserve, history of heart failure. Should not be used in cardiogenic shock, MI, or in acute unstable angina; angina attack in chronic stable angina. Risk of developing heart failure in patients w/ severe aortic stenosis. Avoid abrupt w/drawal. Discontinue if ischaemic pain occurred.
Adverse Reactions
Dizziness, headache, & dose-related orthostatic hypotension.
Drug Interactions
Decreased conc w/ rifampicin. Decreased active metabolite conc & increased losartan conc w/ fluconazole. Increase in serum K w/ K-sparing diuretics, K supplements, or salt substitutes containing K. Reduced excretion of lithium. Further deterioration of renal function & may diminish the antihypertensive effect of losartan w/ NSAIDs including selective COX-2 inhibitors.
MIMS Class
Angiotensin II Antagonists / Calcium Antagonists
ATC Classification
C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Amlotitan FC tab
Packing/Price
30's (P15.75/film-coated tab, P472.5/box)
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