Laboratorios Silesia


JF Draf
Concise Prescribing Info
Fluoxetine HCl
Treatment of depression due to various origins eg, endogenous, neurotic & reactive depressions. Decreases incidence of bulimic attacks; treatment of associated symptoms eg, wt loss (self-induced vomiting, abuse of laxatives). Treatment of obsessive-compulsive disorders which are identified by persisting obsession, thoughts, perception &/or repeated intentional marked compulsive behaviour.
Dosage/Direction for Use
Adult Depression 20 mg daily. Max: 80 mg daily. Doses >20 mg should be given in 2 divided doses (eg, morning & evening). Obsessive-compulsive disorder Initially 20 mg daily, may be increased to 60 mg daily after several wk. Bulimia nervosa 60 mg daily. Elderly & patient w/ low body wt Max of 60 mg.
May be taken with or without food.
Hypersensitivity. Concomitant use w/ MAOIs.
Special Precautions
Anxiety or marked sleeping difficulties at the start of therapy. Patients w/ existing or history of epilepsy; severe hepatic & renal impairment; diabetes; patients taking drugs acting on CNS; patients w/ suicidal tendencies. Discontinue if rash & possible allergic events occur. May cause significant wt loss. May impair ability to drive or operate machinery. Pregnancy (especially during 1st trimester) & lactation. Childn.
Adverse Reactions
Chills & fever, fatigue, asthenia, face edema; nausea & vomiting, disturbance of appetite, diarrhea; headache, nervousness, agitation, visual disturbances, insomnia, anxiety, dizziness; UTI, sexual dysfunction, painful menstruation; dyspnea, bronchitis; acne, alopecia, dry skin, eczema; back, joint & muscle pain.
Drug Interactions
Increased risk of severe adverse events w/ MAOIs. May interfere w/ tryptophan, TCAs, carbamazepine, haloperidol, phenothiazine, other CNS active drugs eg, lithium.
MIMS Class
ATC Classification
N06AB03 - fluoxetine ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Drafzin cap 20 mg
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