Getryl

Getryl

glimepiride

Manufacturer:

Getz Pharma

Distributor:

Getz Bros
Concise Prescribing Info
Contents
Glimepiride
Indications/Uses
Treatment of NIDDM either alone, w/ metformin or w/ insulin whose hyperglycemia cannot be controlled by diet & exercise alone.
Dosage/Direction for Use
Initial therapy: 1-2 mg once daily. Patient sensitive to hypoglycemics 1 mg once daily & titrated carefully. Max starting dose: >2 mg. Maintenance: 1-4 mg once daily. Max: 8 mg once daily. Upon reaching 2 mg, dose is increased in not more than 2-mg increments at 1-2 wk intervals based on patient's blood glucose response. Monitor HbA1c levels every 3-6 mth. Getryl-metformin combination therapy Adjust the dose of each drug. Getryl-insulin combination therapy Initially, Getryl 8 mg once daily. Start w/ low-dose insulin & do upward adjustments wkly as guided by frequent measurements of fasting blood glucose.
Administration
Should be taken with food: Take immediately before 1st main meal of the day.
Contraindications
Diabetic ketoacidosis w/ or w/o coma.
Special Precautions
Monitor fasting blood glucose and HbA1c periodically to determine doses given to patient. Hypoglycemia & loss of control of blood glucose. Pregnancy & lactation. Childn.
Adverse Reactions
Hypoglycemia, visual impairment, GI disturbances, thrombocytopenia, leukopenia, skin allergy, liver impairment, hyponatremia, allergic vasculitis.
Drug Interactions
NSAIDs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid, MAOIs, β-blockers, thiazides, diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, OCs, phenytoin, nicotinic acid, sympathomimetics, INH, rifampicin, fluconazole, amiodarone, tolbutamide, diclofenac, ibuprofen, naproxen, H2-receptor antagonists, clonidine, reserpine, guanethidine. Alcohol.
MIMS Class
ATC Classification
A10BB12 - glimepiride ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.
Presentation/Packing
Form
Getryl tab 4 mg
Packing/Price
20's (P640/pack)
Form
Getryl tab 1 mg
Packing/Price
20's (P250/pack)
Form
Getryl tab 2 mg
Packing/Price
20's (P359.92/pack)
Form
Getryl tab 3 mg
Packing/Price
20's (P440/pack)
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