Zefxon Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Omeprazole

Indications/Uses

Alternative use to oral medication in duodenal & gastric ulcer, reflux oesophagitis, Zollinger-Ellison syndrome, aspiration prophylaxis.

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Dosage/Direction for Use

40 mg IV inj or infusion (20-30 min) once daily. Zollinger-Ellison syndrome 60 mg IV once daily. If higher daily doses are required, the dose should be divided & given bid. Aspiration prophylaxis 40 mg IV 1 hr pre-op.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Exclude malignancy. Pregnancy & lactation. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache, dizziness, paraesthesia, light headedness, faint feeling, somnolence, insomnia, vertigo, reversible mental confusion, agitation, aggression, depression, hallucinations; gynaecomastia; diarrhea, constipation, abdominal pain, nausea, vomiting, flatulence, dry mouth, stomatitis, GI candidiasis; leukopenia, thrombocytopenia, agranulocytosis, pancytopenia; increased liver enzymes, encephalopathy, hepatitis, hepatic failure; arthralgia, myalgia, muscular weakness; impotence; rash/pruritus, urticaria, photosensitivity, bullous eruption, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, alopecia; malaise, hypersensitivity, increased sweating, peripheral edema, blurred vision, taste disturbance, hyponatraemia.

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Drug Interactions

Diazepam, warfarin, phenytoin, disulfiram, other drugs metabolized via CYP450. Decreased absorption of ketoconazole or itraconazole. Increased plasma conc in concomitant use w/ clarithromycin. Increase & decrease in serum cyclosporine conc in concomitant use w/ cyclosporine.

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Storage

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Description

View Zefxon description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antacids, Antireflux Agents & Antiulcerants

ATC Classification

A02BC01 - omeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

Regulatory Classification

Presentation/Packing

Form

Zefxon powd for inj 40 mg

Packing/Price

1's (P588/vial)

Zefxon

omeprazole

Manufacturer:

Biolab

Distributor:

Cathay Drug