Moderate to severe atopic dermatitis in adults & adolescents ≥12 yr who are candidates for systemic therapy. Add-on maintenance treatment for severe asthma w/ type 2 inflammation characterised by raised blood eosinophils &/or raised FeNO in adults & adolescents ≥12 yr who are inadequately controlled w/ high dose inhaled corticosteroid (ICS) plus another medicinal product for maintenance treatment.