Exacerbation of SLE, nephrotic syndrome w/ minimal change lesions, periarteritis nodosa, mixed connective tissue disease, arteritis temporalis; usually in combination w/ adrenaline in anaphylaxis; hypersensitivity reactions to drugs or chemicals, serum sickness, transfusion reactions, insect stings & bites, angioneurotic edema, severe hay-fever, Stevens-Johnson syndrome; combat acute allograft rejection. Adjunct therapy for short-term administration in serious cases of RA & rheumatic OA, synovitis, ankylosing spondylitis, polymyalgia rheumatica, acute rheumatic carditis; local administration in cases of acute & subacute bursitis, synovitis, epicondylitis, tendovaginitis. Primary or secondary adrenocortical insufficiency & adrenogenital syndromes (only if supplemented w/ mineralocorticoid therapy), polycystic ovary syndrome, non suppurative thyroiditis, thyrotoxic crisis; in surgery, severe stress or trauma in cases of decreased or doubtful adrenocortical function. Severe cases of pemphigus & pemphigoid, exfoliative & other serious cases of dermatitis, mycosis, fungoides, erythema multiforme, locally in keloids & some cases of alopecia aerata. Severe acute or chronic allergic inflammatory processes of the eye and its adnexa (subconjunctivally, retrobulbarly or systematically) eg, allergic conjunctivitis, iritis, iridocyclitis, choroiditis, optic neuritis, sympathetic ophthalmia, scar-prevention in the eye surgery & eye injuries. Induce remission of ulcerative colitis & regional enteritis; some cases of chronic hepatitis, especially the aggressive form w/ hyperimmunity; esophagitis corrosiva, some cases of coeliac disease, eosinophilic (gastro) enteritis. Pericarditis (idiopathic, post MI & post commissurotomic syndrome). Asthmatic pulmonary eosinophilia & allergic alveolitis, aspiration pneumonitis, severe bronchial asthma & other chronic nonspecific obstructive lung disease; diffuse interstitial pulmonary processes; as part of the treatment of laryngotracheobronchitis & resp distress syndrome in adults; in combination w/ tuberculostatic therapy in fulminating TB. Idiopathic & secondary thrombocytopenia purpura (IV) only, autoimmunehemolytic anemia, idiopathic immunogranulocytopenia (agranulocytosis), acute & chronic lymphocytic leukemia, acute myelocytic leukemia (blastemic crisis), Hodgkin's disease, other malignancies of the lymphoid & hystocytic tissue, multiple myeloma, advanced myeloma refractory to alkylating agents, macroglobulinemia; as antiemetic in antineoplastic regimens; palliative treatment in terminal stages of neoplastic disease. Cerebral edema particularly those forms resulting from brain tumors, brain abscesses & neurosurgical interventions (in the latter case, also for prevention of brain edema); myoclonic seizures in epilepsy, pseudotumor cerebri, severe myasthenia gravis resistant to anticholinesterase therapy & thymectomy, in some cases of acute multiple sclerosis & peripheral neuritis; acute mountain sickness. Prevention of inflammatory edema & adhesions in surgery; in most cases of TB meningitis, pericarditis, peritonitis & pleuritis (in combination w/ tubercolostatic therapy); antenatal, in the prevention of neonatal resp distress syndrome; severe trichinosis, hypercalcemia eg, associated w/ antineoplastic diseases, hypervitaminosis-D, idiopathic infantile hypercalcemia.