Dexamet Indications/Uses





Full Prescribing Info
Dexamethasone injection may be indicated in the following conditions, especially if oral therapy is not feasible: Immuno-allergology: In some cases, especially in exacerbation of systemic lupus erythematosus, nephrotic syndrome with minimal change lesions, periarteritis nodosa, mixed connective tissue disease, arteritis temporalis; usually in combination with adrenaline in anaphylaxis; hypersensitivity reactions to drugs or chemicals, serum sickness, transfusion reactions, insect stings and bites, angioneurotic edema, severe hay-fever, Steven-Johnson syndrome; to combat acute allograft rejection; Rheumatology: In general as adjunct therapy for short term administration (either systemically or locally) in serious cases of rheumatoid arthritis and rheumatic osteoarthritis, synovitis, ankylosing spondylitis, polymyalgia rheumatica, acute rheumatic carditis; for local administration in cases of acute and subacute bursitis, synovitis, epicondylitis, tendovaginitis; Endocrinology: Primary or secondary adrenocortical insufficiency and adrenogenital syndromes (only if supplemented with mineralocorticoid therapy), polycystic ovary syndrome, non suppurative thyroiditis, thyrotoxic crisis; in surgery, severe stress or trauma in cases of decreased or doubtful adrenocortical function; Dermatology: Severe cases of pemphigus and pemphigoid, exfoliative and other serious cases of dermatitis, mycosis, fungoides, erythema multiforme, locally in keloids and some cases of alopecia aerata; Ophthalmology: Severe acute or chronic allergic inflammatory processes of the eye and its adnexa (subconjunctivally, retrobulbarly or systematically) such as allergic conjunctivitis, iritis, iridocyclitis, choroiditis, optic neuritis, sympathetic ophthalmia, scar-prevention in the eye surgery and eye injuries; Gastro-enterology: To induce remission of ulcerative colitis and regional enteritis; in some cases of chronic hepatitis, especially the aggressive form with hyperimmunity; esophagitis corrosiva, in some cases of coeliac disease, eosinophilic (gastro) enteritis; Cardiology: In some cases of pericarditis (idiopathic, post myocardial infarction and post commissurotomic syndrome); Pulmonology: Asthmatic pulmonary eosinophilia and allergic alveolitis, aspiration pneumonitis, severe bronchial asthma and other chronic nonspecific obstructive lung disease; diffuse interstitial pulmonary processes; as part of the treatment of laryngotracheobronchitis and the respiratory distress syndrome in adults; in combination with tuberculostatic therapy in fulminating tuberculosis; Hematology and Oncology: Idiopathic and secondary thrombocytopenia purpura (IV) only, autoimmune hemolytic anemia, idiopathic immunogranulocytopenia (agranulocytosis), acute and chronic lymphocytic leukemia, acute myelocytic leukemia (blastemic crisis), Hodgkin's disease, other malignancies of the lymphoid and hystocytic tissue, multiple myeloma, advanced myeloma refractory to alkylating agents, macroglobulinemia; as antiemetic in antineoplastic regimens; for palliative treatment in terminal stages of neoplastic disease; Neurology: Cerebral edema particularly those forms resulting from brain tumors, brain abscesses and neurosurgical interventions (in the latter case, also for prevention of brain edema); myoclonic seizures in epilepsy, pseudotumor cerebri, severe myasthenia gravis resistant to anticholinesterase therapy and thymectomy, in some cases of acute multiple sclerosis and peripheral neuritis; acute mountain sickness; Other Indications: In the prevention of inflammatory edema and adhesions in surgery; in most cases of tuberculosis meningitis, pericarditis, peritonitis and pleuritis (in combination with tuberculostatic therapy); antenatal, in the prevention of neonatal respiratory distress syndrome; severe trichinosis, hypercalcemia, e.g. associated with antineoplastic diseases, hypervitaminosis-D, idiopathic infantile hypercalcemia.
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